Muramasa was my introduction to Vanillaware games and holds a special place in my heart. There is technically an enhanced Vita port in the form of Muramasa: Rebirth, but I'm putting my experience here since this entry had more votes.
I desperately want Vanillaware PC ports and honestly you can't go wrong with any of them, but I'd like to bring some older games forward first. Muramasa is stuck on the Wii and Vita.