flv2358: Yup, this works. What I mean is that in the menu, they always stay reversed e.g. I'm right clicking to select inventory items, menus etc.
Got it. So it isn't consistent in the menus and ingame. Okay, that is really weird.
I'm not lefthanded, so no personal experience on this, but from what I do know the ingame settings should be handled by the game (which does work), but the menus and anything "outside" the game (in any game) should be handled by the Windows settings (which doesn't work).
This is either a bug, or an incredible oversight by the developer team. No excuse that they didn't have any lefthanded programmers on staff, because this should have been considered long ago, or since implemented.
In this case, sorry, I don't know how to fix it.
There could be something here:
https://www.reddit.com/r/cyberpunkgame/comments/ka504y/how_to_rebind_the_unrebindable_controls/
...but I can't read Cyberpunk 2077 Reddit properly, because they - in their infinite uselessness - have decided to mark everything Cyberpunk 2077 as "adult content", which requires an account.
The .xml-file referred to above can be opened with a text reader, like Notepad++.
EDIT:
I forgot to add the name and location of the file:
inputUserMappings.xml
...located in:
[X]:\Cyberpunk 2077\r6\config