What is the funniest thing you have ever heard a NPC/Monster say? For me, so far, it was when I was playing Tomb Raider. I just destroyed this elevator a made a huge goddamn racket. I hear an NPC in the background, "Huh? What was that? ....Aw, f- it, I don't want to be here anyway".

Nobody but Danes got it, but in the asylum level in the original Hitman: Codename 47, the "inmates" run around saying "Aggemaaam?" This was actually a sample from a recurring sketch in a Danish radio comedy show at the time. I imagine that most foreigners playing the game just went "Huh? That's gibberish", but Danish players laughed their asses off :-D

Everything the undercover G-Men say in Psychonauts' Milkman Conspiracy level.

http://en.wikiquote.org/wiki/Psychonauts#The_Milkman_Conspiracy

"Although over time, my husband will desire me less, sexually, he will always enjoy my pies."

Streaking in saint's row 2.

random woman: "I've seen bigger on a squirrel."

Off the top of my head I always liked this bit from Splinter Cell: Pandora Tomorrow:
Korean Soldier: "Some kind of American commando!"

Something about the delivery of the line and the fact that you're feeling like a total badass at this point in the game makes it so memorable.


Okay, for one that's a lot more inappropriate:

GTA V: The first time Lamar says... <i><span class="bold">The N Word</span></i>

Morte: "Women were the reason I became a monk - and, ah, the reason I switched back..."
and 90% of the rest that he says...

Random thug walking down the street in The Witcher: "My balls itch."

NOLF : "No you want a nice massage ?"

Giants Citizen Kabuto : "YEEAAAAAAH and there's MORE where that came from !"

PoR: Ruins of Myth Drannor, when confronted by a pair of dark nagas guarding a temple:

"By the gods! Why couldn't there be three of you, or six, or nine? Kog will not be pleased."

VIrgil from Arcanum, with follower taunts on:

"Way to hit those bast—! I mean, good shot, sir."

A few years ago i was running around Los Santos in GTA: San Andreas. I bumped into a guy who looked like a "latino" and he said:

"Your Sister wanted no foreplay!"

*lol*

I remember playing Worms Armageddon with danish speech for the first time against some of my friends.
We laughed so hard that we almost wasn't able to play the game.

http://www.youtube.com/watch?v=9P39ewQ9GUI

Some floating text in Fallout:tactics is quite ... awesome.


War for instance .... never gets old :)

NOLF:

Dmitrij Volkov: Keep your men out of sight. We don't want to spoil our trap, do we?

HARM Agent: Yes sir! I mean, no sir! I mean, yes to the first part and no to the second part, SIR!

Dmitrij Volkov: Shut up. Just do as I say, you idiot.

When the certain death of everyone looms ever closer, the only rational thing to do is to loudly announce the most embarrassing things about yourself. In Saints Row: The Third, my character shouted "I'm in a co-ed Curling team!" at the top of her voice.